CAS NO: | 76095-16-4 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
10 g | 电议 |
50 g | 电议 |
生物活性 | Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is anangiotensin-converting enzyme (ACE) inhibitor. | ||||||||||||||||
IC50& Target | ACE[1]. | ||||||||||||||||
体内研究 (In Vivo) | Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 492.52 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C24H32N2O9 | ||||||||||||||||
CAS 号 | 76095-16-4 | ||||||||||||||||
中文名称 | 马来酸依那普利 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : ≥ 50 mg/mL(101.52 mM) H2O : 33.33 mg/mL(67.67 mM;Need ultrasonic and warming) *"≥" means soluble, but saturation unknown. 配制储备液
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