CAS NO: | 692269-09-3 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | CM10 is a potent and selectivealdehyde dehydrogenase1A (ALDH1A) familyinhibitor, withIC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM10 does not inhibit any of the other ALDH family members. CM10 can regulate metabolism and has anti-cancer activity[1]. | ||||||||||||||||
IC50& Target | IC50: 1700 nM (ALDH1A1), 740 nM (ALDH1A2) and 640 nM (ALDH1A3)[1] | ||||||||||||||||
体外研究 (In Vitro) | CM10 (12.5, 25, 50, 100 μM; 1 hour) inhibits ALDEFLUOR activity in live cells and preferentially depletes CD133+ovarian cancer stem-like cells (CSCs)[1]. | ||||||||||||||||
分子量 | 321.42 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C20H23N3O | ||||||||||||||||
CAS 号 | 692269-09-3 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 125 mg/mL(388.90 mM;Need ultrasonic) 配制储备液
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