您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > IGUANA-1 free base
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
IGUANA-1 free base
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IGUANA-1 free base图片
CAS NO:2756014-24-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
STL5-T-0057
产品介绍
IGUANA-1 free base (STL5-T-0057) 是ALDH1 B1的选择性抑制剂,IC50值为 30 nM。IGUANA-1 free base 抑制 SW480 细胞生长在附着或球形条件下,IC50值分别为 2.46 和 0.39 μM。IGUANA-1 free base 可用于癌症的研究。
生物活性

IGUANA-1 free base (STL5-T-0057) is an selectiveALDH1B1inhibitor with anIC50value of 30 nM. IGUANA-1 free base inhibits cell growth of SW480 cells in adherent and spheroid conditions withIC50values of 2.46 and 0.39 μM, respectively. IGUANA-1 free base can be used for the research ofcancer[1].

IC50& Target

IC50: 30 nM (ALDH1 B1), 2.46 μM (SW480, adherent), 0.39 μM (SW480, spheroid)[1]

体外研究
(In Vitro)

IGUANA-1 free base (compound 68) (0-10 μM) inhibits ALDH1 B1 with an IC50value of 30 nM[1].
IGUANA-1 free base (0.01-10 μM; 4-5 d) inhibits cell growth of HEK293T cells[1].
IGUANA-1 free base (0.01-10 μM) inhibits cell viability of SW480 cells in adherent and spheroid conditions with IC50values of 2.46 and 0.39 μM, respectively[1].

Cell Cytotoxicity Assay[1]

Cell Line:HEK293T cell line
Concentration:0.01-10 μM
Incubation Time:4-5 d
Result:Showed cell cytotoxicity to HEK293T cells with a GI50value of 1.7 μM.
分子量

445.94

Formula

C26H24ClN3O2

CAS 号

2756014-24-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.