CAS NO: | 222989-99-3 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Finasteride (MK-906) acetate is a potent and competitive5α-reductaseinhibitor, with anIC50of 4.2 nM for type II 5α-reductase. Finasteride acetate has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride acetate can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia[1][2][3]. | ||||||||
IC50& Target | IC50: 4.2 nM (type II 5α-reductase)[1] | ||||||||
体外研究 (In Vitro) | Finasteride (10 μM; 6-24 h) induces the expression of HO-1 and Nrf2 proteins in PC-3 cells[2]. Cell Viability Assay[2]
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体内研究 (In Vivo) | Finasteride (0.1-0.5 mg/kg; p.o. once daily for 16 weeks) reduces prostatic size in dogs with BPH without adversely affecting semen quality or serum testosterone concentration[3].
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Clinical Trial | |||||||||
分子量 | 432.60 | ||||||||
Formula | C25H40N2O4 | ||||||||
CAS 号 | 222989-99-3 | ||||||||
中文名称 | 醋酸非那雄胺;醋酸非那斯特萊 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |