CAS NO: | 187870-78-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | Rimeporide (EMD-87580) is a potent and selective inhibitor of theNa+/H+exchanger (NHE-1). | ||||||||||||||||
IC50& Target | NHE1[1] | ||||||||||||||||
体外研究 (In Vitro) | Blocking NHE-1 activity has been shown to decrease intracellular Na+and Ca2+overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 333.38 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C11H15N3O5S2 | ||||||||||||||||
CAS 号 | 187870-78-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 20 mg/mL(59.99 mM;Need ultrasonic and warming) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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