CAS NO: | 852146-73-7 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | KR-32568 is asodium/hydrogen exchanger-1 (NHE-1)inhibitor with anIC50of 230 nM. KR-32568 has cardioprotective effects[1][2]. | ||||||||
IC50& Target | IC50: 230 nM (NHE-1)[2] | ||||||||
体外研究 (In Vitro) | KR-32568 (10 nM-1 μM) 以浓度依赖性方式抑制 NHE-1 介导的兔富血小板血浆细胞内酸化引起的血小板肿胀,IC50值为 24 nM[1]。 | ||||||||
体内研究 (In Vivo) | KR-32568(0.1-1.0 mg/kg;i.v.;一次)对大鼠发挥有效的心脏保护作用,例如减少梗塞面积,并显着减少室性早搏的总数[1]。
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分子量 | 261.25 | ||||||||
Formula | C13H12FN3O2 | ||||||||
CAS 号 | 852146-73-7 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |