CAS NO: | 2750001-23-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
生物活性 | AZD0095 is a selective and orally activeMCT4inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination withCediranib(HY-10205)[1]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | AZD0095 (0-50 μM) 抑制 NCI-H358 细胞 (MCT4 高表达) 的增殖,IC50为 26 nM[1]。 | ||||||||
体内研究 (In Vivo) | AZD0095 (100 mg/kg, 口服,一天两次) 与Cediranib(HY-10205) 联合使用抑制小鼠 NCI-H358 异种移植肿瘤的生长[1]。
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分子量 | 500.60 | ||||||||
Formula | C27H32N8O2 | ||||||||
CAS 号 | 2750001-23-9 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |