Ifenprodil tartrate is a typical noncompetitiveNMDAreceptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM)^[1]. Ifenprodil tartrate inhibitsGIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator^[2].

IC50: 0.34 μM (NR1A/NR2B receptor); 146 μM (NR1A/NR2A receptor)^[1]

G protein-activated inwardly rectifying K+ channels (GIRK)^[1].

400.49

Solid

C₂₅H₃₃NO₈

23210-58-4

酒石酸艾芬地尔；苄哌酚胺

• Alkaloids
• Piperidine Alkaloids

• Plants
• Crassulaceae
• Sedum sarmentosumBunge

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

DMSO : ≥ 500 mg/mL(1248.47 mM)

H₂O : 5 mg/mL(12.48 mM;Need ultrasonic)

*"≥" means soluble, but saturation unknown.

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

• 1.

  请依序添加每种溶剂： 0.5%CMC-Na/saline water

  Solubility: 12.22 mg/mL (30.51 mM); Suspended solution; Need ultrasonic
• 2.

  请依序添加每种溶剂： 1% DMSO   99% saline

  Solubility: ≥ 1 mg/mL (2.50 mM); Clear solution