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Stearoyl-L-carnitine chloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Stearoyl-L-carnitine chloride图片
CAS NO:32350-57-5
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
Stearoyl-L-carnitine chloride 是一种内源性的长链酰基肉碱。Stearoyl-L-carnitine chloride 是一种效力较弱的GlyT2抑制剂。Stearoyl-L-carnitine chloride 在浓度高达 3 μM 时可抑制 16.8％ 的甘氨酸响应。
生物活性

Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor ofGlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].

IC50& Target[2]

GlyT2

 

体外研究
(In Vitro)

Stearoyl-L-carnitine (0.01-10 μM) inhibits glycine (30 μM) transports by 16.8% at concentrations up 3 μM inXenopus laevisoocytes[2].
Stearoyl-L-carnitine (500 μM; 30 min) inhibits Na+-dependent [3H]carnitine (20 nM) uptake by ~50% in HPCT cells[3].

体内研究
(In Vivo)

Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC)[1].

分子量

464.12

性状

Solid

Formula

C25H50ClNO4

CAS 号

32350-57-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)