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Abiraterone metabolite 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Abiraterone metabolite 1图片
CAS NO:1940176-03-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Abiraterone metabolite 1 是 abiraterone 的 5β-还原代谢物。Abiraterone 是一种甾体药物,可抑制 CYP17A1,阻断雄激素的合成,延长前列腺癌的生存期。
Cas No.1940176-03-3
别名3β-OH-5α-Abi
Canonical SMILESC[C@@]12C(C3=CN=CC=C3)=CC[C@]1([C@@]4(CC[C@@]5([H])[C@@](C)([C@]4(CC2)[H])CC[C@@H](C5)O)[H])[H]
分子式C24H33NO
分子量351.52
溶解度DMSO: ≥ 25 mg/mL (71.12 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal drug, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer.

[1]. Li Z, et al. Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy. Nature. 2016 May 26;533(7604):547-51.