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Carboxypeptidase G2(CPG2)Inhibitor
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Carboxypeptidase G2(CPG2)Inhibitor图片
CAS NO:192203-60-4
包装与价格：
包装价格(元)
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Carboxypeptidase G2 (CPG2) Inhibitor是羧肽酶G2（CPG2）抑制剂，具有抗癌活性。
Cas No.192203-60-4
别名N-[[(4-甲氧基苯基)硫]羰基]-L-谷氨酸,CPG2 Inhibitor
Canonical SMILESO=C(SC(C=C1)=CC=C1OC)N[C@@H](CCC(O)=O)C(O)=O
分子式C13H15NO6S
分子量313.33
溶解度Water: 1.43 mg/mL (4.56 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.

[1]. Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956. [2]. Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66. [3]. Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55. [4]. Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8.