| Cas No. | 77879-89-1 |
| 别名 | 古铜色菌素M |
| Canonical SMILES | O=C(O1)C2=C(C(OC)=CC(C)=C2)C3=C1C4=C([C@H]5O[C@@]([H])([C@H](O)C)[C@H](O)[C@H]5O)C=CC(O)=C4C(OC)=C3 |
| 分子式 | C26H26O9 |
| 分子量 | 482.5 |
| 溶解度 | DMF: soluble,DMSO: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 µg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 µg/ml) but has no effect on survival in a P388 mouse model of leukemia when used at doses ranging from 25 to 400 mg/kg. Gilvocarcin M intercalates into bacteriophage PM2 DNA. It is toxic to rats with an intravenous LD50 value of 450 mg/kg. |
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