Fulvic acid is a phenolic acid and fungal metabolite originally isolated from Penicillium. Fulvic acids are formed via degradation of organisms and their wastes and are classified as humic substances, which are present in soil and water, can form complexes with metals, and can act as oxidizers or reducers. Fulvic acid is predicted to inhibit amyloid-β (17-42) (Aβ17-42) dimerization, disrupt preformed Aβ17-42 trimers, and bind to the catalytic site of phosphodiesterase 5A (PDE5A) based on molecular dynamics simulation studies.