| CAS NO: | 194874-06-1 |
| 包装: | 100 μg |
| 市场价: | 6500元 |
| 生物活性 | Apoptolidin is a polyketide isolated fromNocardiopsis bacteria[1]. Apoptolidin is a selective mitochondrialF1FOATPaseinhibitor. Apoptolidin is anapoptosisinducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells[1][2]. | |||||||||
| 体外研究 (In Vitro) | Apoptolidin has cytotoxicity against normal and transformed cells, it against RG-E1A-7,RG-E1A19K-2, RG-E1A54K-9, RG-E1-4 and Adl2-3Y1 with IC50values of 11 ng/ml,10 ng/ml,13 ng/ml, 10 ng/ml and 17 ng/ml, respectively[1]. | |||||||||
| 分子量 | 1129.37 | |||||||||
| 性状 | Solid | |||||||||
| Formula | C58H96O21 | |||||||||
| CAS 号 | 194874-06-1 | |||||||||
| 结构分类 |
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| 来源 | Nocardiopsis | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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