CAS NO: | 11076-19-0 |
包装: | 500 μg |
市场价: | 11500元 |
生物活性 | Bongkrekic acid is amitochondrial toxinsecreted by the bacteriaPseudomonas cocovenenans[1]. Bongkrekic acid specific ligand for mitochondrialadenine nucleotide translocase (ANT)rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport[2]. | |||||||||
体外研究 (In Vitro) | Bongkrekic acid (0-50 μM; 48 hours) stimulated formazan formation in MDA-MB-231, MCF-7 and LTED cells with EC50of 34.14 μM, >50 μM and 2.58 μM, respectively.Bongkrekic acid (0.1-25 μM; 48 hours) decreases the living cell numbers in LTED cells and parent MCF-7 cells in a dose-dependent manner[1]. | |||||||||
分子量 | 486.60 | |||||||||
性状 | Solid | |||||||||
Formula | C28H38O7 | |||||||||
CAS 号 | 11076-19-0 | |||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
储存方式 |
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