| CAS NO: | 25952-53-8 |
| 包装: | 10g |
| 市场价: | 683元 |
| Cas No. | 25952-53-8 |
| 别名 | 1-乙基-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 |
| 化学名 | 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride |
| Canonical SMILES | CCN=C=NCCCN(C)C.Cl |
| 分子式 | C8H17N3.HCl |
| 分子量 | 191.7 |
| 溶解度 | ≥ 19.2 mg/mL in DMSO, ≥ 39.6 mg/mL in ETOH, ≥ 39 mg/mL in Water |
| 储存条件 | Store at -20°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | IC50: Not available. EDC.HCl, which is commonly regarded as carbodiimide reagents, serves as a very useful tool for the formation of amide bonds (peptide bonds) in an aqueous medium. As one of the carbodiimide reagents, it is also effectively applied in anhydroxydation, polynucleotide synthesis, esterification and lactonization.In addition, EDC.HCl is also widely used as water soluble condensing reagent. [1] In vitro: Carbodiimide-mediated coupling method was one of the most traditional approaches for peptide-bond formation. With the aim to synthesis target compounds, carbodiimide reagents were added after thoroughly mixing of a carboxylic acid and an amine. After the reaction was accomplished, the carbodiimide reagent was then changed into its corresponding urea. [2] Recently, a simple and fast detection method using spectrophotometric flow injection analysis was developed. This method was based on the reaction between EDC.HCl and pyridine in acidic aqueous solution. After reaction at 40C for a while, the absorbance was measured at 400 nm. The calibration curve demonstrated a good linearity from 0 to 10% of EDC·HCl solutions with the following regression equation: y = 3.15 × 104x (x, % concentration of EDC·HCl; y, peak area). This approach served to monitoring the concentration of EDC·HCl after its reaction in water. [1] In vivo: So far, no in vivo data has been reported. Clinical trial: So far, no clinical trial has been conducted. References: |
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