PD 123319 ditrifluoroacetate

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

130663-39-7

包装与价格：

包装	价格(元)
10mg	电议
25mg	电议
50mg	电议
100mg	电议
10mM * 1mL in DMSO	电议

产品名称

PD123319, PD-123319

产品介绍

生物活性

PD 123319 ditrifluoroacetate是一种有效的，选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。

靶点信息

AT2 receptor
34 nM

化学数据

目录号	A13201
作用机制	Antagonist (拮抗剂)
M. Wt	736.67
Formula	C31H32N4O3.2CF3CO2H
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	130663-39-7
Synonyms	PD123319, PD-123319
SMILES	CC1=C(C=CC(=C1)CN2C=NC3=C2C[C@H](N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C

溶解度

In vitro (25°C)	DMSO	87 mg/mL (171.05 mM)
	Water	87 mg/mL (171.05 mM)
	Ethanol	87 mg/mL (171.05 mM)
In vivo	Saline	28 mg/mL
<1 mg/ml means slightly soluble or insoluble. Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.57 mL	67.87 mL	135.75 mL
0.5 mM	2.71 mL	13.57 mL	27.15 mL
1 mM	1.36 mL	6.79 mL	13.57 mL
5 mM	0.27 mL	1.36 mL	2.71 mL

*The above data is based on the productmolecular weight 736.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.