CAS NO: | 485-63-2 |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | 7,3',4'-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor ofCot (Tpl2/MAP3K8)andMKK4. 7,3',4'-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | 7,3',4'-Trihydroxyisoflavone triggers cell cycle arrest at the G1 phase and displays an anti-proliferative effect against EGF receptor-positive skin cancer[1]. | ||||||||||||||||
体内研究 (In Vivo) | In a mouse skin tumorigenesis model, 7,3',4'-Trihydroxyisoflavone strongly suppresses the incidence, multiplicity, and volume of UVB-induced mouse skin tumors. Consistent with the tumor data, 7,3',4'-Trihydroxyisoflavone clearly attenuates UVB-induced COX-2 expression in hairless mouse skin[2]. | ||||||||||||||||
分子量 | 270.24 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C15H10O5 | ||||||||||||||||
CAS 号 | 485-63-2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 125 mg/mL(462.55 mM) *"≥" means soluble, but saturation unknown. 配制储备液
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