CAS NO: | 724453-98-9 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Diflapolin is a highly active dual 5-lipoxygenase-activating protein(FLAP)/solubleepoxide hydrolase(sEH)inhibitor with marked anti-inflammatory efficacy and high target selectivity. Diflapolin inhibits5-LOXproduct formation in intact human monocytes and neutrophils withIC50s of 30 and 170 nM, respectively, and suppressed the activity of isolated sEH (IC50=20 nM)[1]. | ||||||||||||||||
体内研究 (In Vivo) | Diflapolin (1-10 mg/kg; i.p.; 30 min before zymosan injection) exhibits potent anti-inflammatory properties in in-vivo experiments[1].
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分子量 | 458.36 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C22H17Cl2N3O2S | ||||||||||||||||
CAS 号 | 724453-98-9 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 83.33 mg/mL(181.80 mM;Need ultrasonic) 配制储备液
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