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Vilobelimab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2250440-41-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
CaCP-29, IFX-1
产品介绍
Vilobelimab (CaCP-29, IFX-1) 是一种单克隆抗C5a抗体,过敏毒素 C5a 是一种促炎补体分裂产物,在介导器官功能障碍中起核心作用。Vilobelimab 可作为一种 C5a 抑制剂,抑制中性粒细胞活化、趋化性,减少炎症信号等,可用于败血症,COVID-19 等相关研究。
生物活性

Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5aantibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc[1].

体外研究
(In Vitro)

Vilobelimab selectively neutralises C5a in a dose-dependent manner without blocking the formation of the membrane attack complex and without leading to detectable safety concerns In certain clinical studies of patients suffering from severe sepsis and septic shock[1].

CAS 号

2250440-41-4

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.