包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | AB-680 ammonium is a highly potent, reversible and selective inhibitor ofCD73(an ecto-nucleotidase), with aKiof 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidasesCD39. Anti-tumor activity[1]. |
IC50& Target | Ki: 4.9 pM (hCD73)[1] |
体外研究 (In Vitro) | AB-680 ammonium inhibits soluble hCD73 with an IC50of 0.043 nM, also inhibits hCD73 in CHO cells, suppresses CD73 in human, mouse CD8+T Cells and hPBMC, with IC50s of 0.070, 0.008, 0.66 and 0.011 nM, respectively[1]. |
Clinical Trial | |
分子量 | 614.89 |
Formula | C20H30ClFN6O9P2 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |