CCG-273463 is a potent, selective and covalentGRK5inhibitor with anIC₅₀value of 8.6 nM. CCG-273463 can be used in the research of heart failure, hypertrophic cardiomyopathy, andcancer^[1].

IC50: 8.6 nM (GRK5), 12 μM (GRK2)^[1].

CCG-273463 (0.02-1 μM) potently and highly inhibits GRK5 (IC₅₀: 8.6 nM), with inhibitory rate of 93% (GRK5) and 97% (GRK6) at 1 μM^[1].

521.41

C₂₆H₂₅BrN₄O₃

2750413-99-9

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.