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Deoxycholic acid sodium hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Deoxycholic acid sodium hydrate图片
CAS NO:145224-92-6
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Cholanoic Acid sodium hydrate
Desoxycholic acid sodium hydrate
产品介绍
Deoxycholic acid (cholanoic acid) sodium hydrate 是一种胆汁酸,肠道代谢副产物,可以激活 G 蛋白偶联胆汁酸受体TGR5
生物活性

Deoxycholic acid (cholanoic acid) sodium hydrate,a bile acid, is a by-product of intestinal metabolism, that activates theG protein-coupled bile acid receptorTGR5[1][2].

IC50& Target

Microbial Metabolite

 

体外研究
(In Vitro)

Deoxycholic acid sodium hydrate (DCA) (100 μM) induces the production of gastric cancer cell line MGC803 resistant to acidified bile acids and enhances their survival and proliferation activity under bile acid stress[2].
Deoxycholic acid sodium hydrate (DCA) (100 μM)-induced resistant cells shows altered morphology, significantly elevated telomerase activity, better cell viability and reduces apoptosis compared to normal MGC803 cells[2].

Clinical Trial
分子量

432.57

Formula

C24H41NaO5

CAS 号

145224-92-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.