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Sarafotoxin S6c
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:121695-87-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
SRTX-c
产品介绍
Sarafotoxin S6c (SRTX-c) 是一种有效的内皮素B受体 (endothelin-B receptor) 激动剂。Sarafotoxin S6c 可引起内皮完好血管和内皮剥离血管的收缩。
生物活性

Sarafotoxin S6c (SRTX-c) is a potentendothelin-B receptoragonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1].

IC50& Target

Endothelin-B receptor[1]

体内研究
(In Vivo)

Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1].

Animal Model:Male Wister rats, exposed to 10% O2[chronic hypoxic (CH) rats] or room air (control rats) for 2 weeks[1]
Dosage:1 pM-1 mM
Administration:
Result:Chronic hypoxia had effect on the sensitivity of the main pulmonary arteries to SCS6c, and small vasoconstrictor responses to were evident.
Caused vasoconstriction with a maximum response 30% of that to ET-1 in both endothelium-intact and endothelium-denuded vessels.
分子量

2515.75

Formula

C103H147N27O37S5

CAS 号

121695-87-2

Sequence Shortening

CTCNDMTDEECLNFCHQDVIW (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.