CAS NO: | 1597489-14-9 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | ML401, a potent chemical probe, selectively antagonizesEBI2(also known asGPR183) with anIC50of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1]. | ||||||||||||||||
IC50& Target | IC50: 1.03 nM (EBI2)[1] | ||||||||||||||||
体外研究 (In Vitro) | ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM)[1]. | ||||||||||||||||
体内研究 (In Vivo) | ML401 shows very good stability in both human plasma and mouse plasma[1]. | ||||||||||||||||
分子量 | 419.74 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C20H20BrClN2O | ||||||||||||||||
CAS 号 | 1597489-14-9 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 10.42 mg/mL(24.82 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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