CAS NO: | 5928-25-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | Decursin ((+)-Decursin) is a potentanti-tumoragent. Decursin also is a cytotoxic agent and a potentprotein kinase Cactivator. Decursin inducesapoptosisand cell cycle arrest at G1 phase. Decursin decreases the expression ofCDK2,CDK4,CDK6, cyclin D1 protein at 48 h. Decursin inhibits cell proliferation and migration. Decursin shows anti-tumor, anti-inflammatory and analgesic activities[1][2][3][4]. | ||||||||||||||||||||||||
体外研究 (In Vitro) | Decursin (0, 25, 50, 100 μM; 24, 28, 72, 96 h) inhibits cell growth in a dose- and time- dependent manner in DU145 cells[1]. Cell Viability Assay[1]
Cell Cycle Analysis[1]
Western Blot Analysis[1]
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体内研究 (In Vivo) | Decursin (4 mg/kg; s.c.; daily for 4 weeks) shows anti-tumor activity in mouse[2].
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分子量 | 328.36 | ||||||||||||||||||||||||
性状 | Solid | ||||||||||||||||||||||||
Formula | C19H20O5 | ||||||||||||||||||||||||
CAS 号 | 5928-25-6 | ||||||||||||||||||||||||
中文名称 | 紫花前胡素 | ||||||||||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||||||||||
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||||||||||
溶解性数据 | In Vitro: DMSO : 50 mg/mL(152.27 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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