CAS NO: | 159899-65-7 |
包装 | 价格(元) |
500 μg | 电议 |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | Adrenomedullin(AM) (22-52), human, an NH2 terminal truncatedadrenomedullinanalogue, is anadrenomedullinreceptorantagonist, and also antagonizes thecalcitoningenerelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat[1][2]. | ||||||||||||||||
IC50& Target | Adrenomedullin receptor, CGRP receptor[1] | ||||||||||||||||
体外研究 (In Vitro) | Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist[1]. | ||||||||||||||||
分子量 | 3576.04 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C159H252N46O48 | ||||||||||||||||
CAS 号 | 159899-65-7 | ||||||||||||||||
Sequence | Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 | ||||||||||||||||
Sequence Shortening | TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 50 mg/mL(13.98 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |