CAS NO: | 164178-33-0 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | 6-Iodopravadoline (AM630) is a selective cannabinoidCB2receptorantagonist (Ki=31.2 nM) that displays 165-fold selectivity overCB1receptors. 6-Iodopravadoline attenuates the ability of a number of cannabinoids to inhibit electrically-evoked twitches of the mouse isolated vas deferens[1][2]. | ||||||||||||||||
IC50& Target | Ki: 31.2 nM (CB2) | ||||||||||||||||
体内研究 (In Vivo) | 6-Iodopravadoline (AM630) (2, 3 mg/kg, i.p.; Swiss ICR mice) significantly reduces the time spent in the light box compared with vehicle group. 6-Iodopravadoline (AM630) (1, 2 or 3 mg/kg, i.p., twice a day; Swiss ICR mice) produces a significant anxiolytic effect, increasing the time spent in the light box at all of the doses used[3]. | ||||||||||||||||
分子量 | 504.36 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C23H25IN2O3 | ||||||||||||||||
CAS 号 | 164178-33-0 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 50 mg/mL(99.14 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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