CAS NO: | 111857-96-6 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | BIM23042, a certain somatostatin (SS) octapeptide analogue, is a selectiveneuropeptide neuromedin B receptor(NMB-R, BB1) antagonist.BIM23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2).BIM23042 inhibitsNeuromedin B (HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca2+release[1][2][3]. | ||||||||
体外研究 (In Vitro) | BIM 23042 (5 μM) 在 huNMBR 细胞中竞争性抑制 Neuromedin B 诱导的 [3H] 花生四烯酸释放,Ki为 49 nM[1]。 | ||||||||
体内研究 (In Vivo) | BIM 23042 (10μg; 静脉给药; 单次推注) 可减轻神经源性肿胀和热和机械致敏[2]。
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分子量 | 1192.45 | ||||||||
Formula | C63H73N11O9S2 | ||||||||
CAS 号 | 111857-96-6 | ||||||||
Sequence Shortening | {DNal}-CY-{DTrp}-KVC-{Nal}-NH2 (Disulfide bridge:Cys2-Cys7) | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |