ML233 is a non-peptide based potentapelin receptor (APJ)agonist (EC₅₀=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM)^[1].

EC50: 3.7 μM (Apelin receptor)^[1]

ML233 shows potentially significant binding against several other receptors, including the 5-HT1A, α2C adrenergic, and benzylpiperazine receptors and norepinephrine transporter. ML233 shows some toxicity (LC₅₀=25.8 μM) toward human hepatocyctes^[1].

359.44

C₁₉H₂₁NO₄S

2080311-92-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.