您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > Y-26763
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Y-26763
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Y-26763图片
CAS NO:127408-31-5
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Y-26763 是一种 K+ 通道开启剂和 Y-27152 的活性代谢物。
Cas No.127408-31-5
化学名N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-hydroxyacetamide
Canonical SMILESO[C@@H]1C(C)(C)OC2=C(C=C(C#N)C=C2)[C@H]1N(C(C)=O)O
分子式C14H16N2O4
分子量276.29
溶解度DMSO: 100 mM,Ethanol: 100 mM
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Y-26763 is a K+ channel opener and active metabolite of Y-27152[1]. Y-26763 is an ATP-sensitive K+ (KATP) channel activator[2].

References:
[1]. Itoh T, et al. Effects of a newly synthesized K+ channel opener, Y-26763, on noradrenaline-induced Ca2+ mobilization in smooth muscle of the rabbit mesenteric artery. Br J Pharmacol. 1994 Jan;111(1):165-72.
[2]. Tran QTN, et al. The identification of naturally occurring labdane diterpenoid calcaratarin D as a potential anti-inflammatory agent. Eur J Med Chem. 2019 Jul 15;174:33-44.