Peptide5, a connexin 43 mimetic peptide, reduceanimalsswelling, astrogliosis, and neuronal cell death after spinal cord injury^[1]

Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner^[1].

Peptide5 is could be used to treat traumatic spinal cord injured rats^[1].

1395.58

C₆₀H₉₈N₁₆O₂₀S

916977-43-0

VDCFLSRPTEKT

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.