CAS NO: | 2707510-30-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | GRP78-IN-3 is a selectiveGrp78 (HSPA5)inhibitor with anIC50of 0.59 μM. GRP78-IN-3 is 7-fold selective forHspA5compared to HspA9 (IC50of 4.3 μM) and >20-fold selective forHspA5compared to HspA2 (IC50of 13.9 μM)[1]. | |
IC50& Target[1] |
| |
体外研究 (In Vitro) | GRP78-IN-3 (compound 8) is a potent small-molecule-competitive inhibitor of Hsp70 substrate binding. GRP78-IN-3 (0.1-100 μM) shows more potent inhibition efffects in a spheroid tumor model (U251 glioblastoma cells and H520 lung cancer cells)[1]. | |
分子量 | 342.42 | |
Formula | C17H18N4O2S | |
CAS 号 | 2707510-30-1 | |
运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |