Org 20599 是一种正变构调节剂,在较高浓度下是 GABAA 受体的直接激动剂,EC50 为 1.1 μM。
Cas No. | 156685-94-8 |
化学名 | 2-chloro-1-((2S,3R,5S,8R,9R,10S,13S,14R,17R)-3-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone |
Canonical SMILES | ClCC([C@H]1[C@]2(C)[C@H](CC1)[C@H]3[C@@H](CC2)[C@](C[C@@H]4N5CCOCC5)(C)[C@H](C[C@H]4O)CC3)=O |
分子式 | C25H40ClNO3 |
分子量 | 438.04 |
溶解度 | <43.8mg/ml in 1eq. HCl;<43.8mg/ml in DMSO |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |