7-Aminoactinomycin D (7-AAD) a fluorescentDNA stain, is a potentRNA polymeraseinhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects^[1][2][3].

7-Aminoactinomycin D (7-AAD) is a DNA dye that distinguishes viable, apoptotic, and late apoptotic/dead cells in flow cytometry. 7-Aminoactinomycin D staining with 5 μg/mL, 10 μg/mL, and 20 μg/mL, but not with 1 μg/mL, is suitable for quantification of apoptosis in flow cytometry^[1].
7-Aminoactinomycin D is frequently used to stain and exclude dead cells in flow cytometry at low concentrations (0.5-5 μg/mL). At higher concentrations (10-20 μg/mL), 7-Aminoactinomycin D has also been used to distinguish between viable cells (7-AAD_negative) and apoptotic cells (7-AAD_dim) or dead cells (7-AAD_bright) using the fact that permeability of the cell membrane, and hence fluorescence intensity, is low in early apoptotic cells and high in late apoptotic and dead cells^[1].

1270.43

Solid

C₆₂H₈₇N₁₃O₁₆

7240-37-1

7-氨基放线菌素D

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。

DMSO : 100 mg/mL(78.71 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。