NFPS 是一种选择性、非竞争性甘氨酸转运蛋白-1 (GlyT1) 抑制剂,对 hGlyT1 和 rGlyT1 的 IC50 分别为 2.8 nM 和 9.8 nM。
Cas No. | 405225-21-0 |
别名 | (Rac)-NFPS |
化学名 | (S)-2-((3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl)(methyl)amino)acetic acid |
Canonical SMILES | FC1=CC=C(C=C1)[C@H](CCN(C)CC(O)=O)OC2=CC=C(C3=CC=CC=C3)C=C2 |
分子式 | C24H24FNO3 |
分子量 | 393.45 |
溶解度 | <3.93mg/ml in DMSO;<1.97mg/ml in ethanol |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |