您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > PD 118057
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PD 118057
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PD 118057图片
CAS NO:313674-97-4
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
PD 118057 是一种 hERG 通道激活剂,不会导致 hERG 阻断。
Cas No.313674-97-4
化学名2-((4-(3,4-dichlorophenethyl)phenyl)amino)benzoic acid
Canonical SMILESClC1=CC(CCC(C=C2)=CC=C2NC3=CC=CC=C3C(O)=O)=CC=C1Cl
分子式C21H17Cl2NO2
分子量386.27
溶解度<38.63mg/ml in DMSO;<7.73mg/ml in ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PD-118057 is a human ether-a-go-go-related gene (hERG) channel activator that does not cause hERG blockade[1].

References:
[1]. Mao H, et al. Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin. PLoS One. 2013 Jun 19;8(6):e65481.