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Disitamab vedotin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2136633-23-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品名称
RC48
产品介绍
Disitamab vedotin (RC48) 是一种抗体-药物偶联物(ADC),包含抗人表皮生长因子受体2(HER2)的单克隆抗体,该单克隆抗体通过可降解连接子结合到细胞毒性剂 MMAE。Disitamab vedotin 增强抗肿瘤免疫。
生物活性

Disitamab vedotin (RC48) is an antibody-drug conjugate(ADC)comprising a monoclonal antibody against human epidermal growth factor receptor 2(HER2)conjugated via acleavablelinker to the cytotoxic agent MonomethylauristatinE (MMAE). Disitamab vedotin enhances antitumor immunity[1].

IC50& Target[1]

HER2

 

体外研究
(In Vitro)

The antibody part was a humanized monoclonal antibody targeting HER2, the small molecule toxin was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease cleavable linker covalently attached MMAE to the antibody[2].

Clinical Trial
性状

Solid

CAS 号

2136633-23-1

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.