CAS NO: | 2136633-23-1 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | Disitamab vedotin (RC48) is an antibody-drug conjugate(ADC)comprising a monoclonal antibody against human epidermal growth factor receptor 2(HER2)conjugated via acleavablelinker to the cytotoxic agent MonomethylauristatinE (MMAE). Disitamab vedotin enhances antitumor immunity[1]. | |
IC50& Target[1] |
| |
体外研究 (In Vitro) | The antibody part was a humanized monoclonal antibody targeting HER2, the small molecule toxin was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease cleavable linker covalently attached MMAE to the antibody[2]. | |
Clinical Trial | ||
性状 | Solid | |
CAS 号 | 2136633-23-1 | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |