Niclofolan

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Niclofolan

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

10331-57-4

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
25mg	电议
50mg	电议
100mg	电议
200mg	电议
500mg	电议

产品名称

BAY 9015
Menichlopholan
Menichlofolan
Bilevon

产品介绍

Niclofolan (BAY 9015) 是一种具有口服活性的驱虫剂。Niclofolan 可用于寄生虫感染相关的研究。

生物活性

Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasiteinfection^[1]^[2]^[3].

体外研究
(In Vitro)

Niclofolan (0.12 mg/mL, 60 min) is effective againstGyrodactylussp. underin vitroconditions^[3].

Cell Viability Assay^[3]

Cell Line:	Gyrodactylussp. (parasite)
Concentration:	0.12 mg/mL
Incubation Time:	60 min
Result:	Reduced the number of liveGyrodactylussp. By 100%.

体内研究
(In Vivo)

Niclofolan (2 mg/kg, intramuscular injection) is effective againstfasciola hepaticainfected sheep^[2].
Niclofolan (1 or 2 mg/kg, oral gavage ) shows therapeutic effects againstP.iloktsuenesisinfected rats^[4].

Animal Model:	fasciola hepaticainfected sheep^[2]
Dosage:	2 mg/kg
Administration:	Intramuscular injection
Result:	Showed effectiveness against the infection and produced no untoward effects except for transient signs of pain at the site of injection.

Animal Model:	Rats infected withP.iloktsuenesis^[4]
Dosage:	1 mg/kg, daily for 3 days; 2 mg/kg every other day for 2 times.
Administration:	Oral gavage
Result:	Reduced the worms in rats.

分子量

345.09

性状

Solid

Formula

C₁₂H₆Cl₂N₂O₆

CAS 号

10331-57-4

中文名称

硝氯酚；羊肝酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO : 100 mg/mL(289.78 mM;Need ultrasonic)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.8978 mL	14.4890 mL	28.9779 mL
5 mM	0.5796 mL	2.8978 mL	5.7956 mL
10 mM	0.2898 mL	1.4489 mL	2.8978 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。