化学性质
| Physical Appearance | A crystalline solid |
| Storage | Store at 4°C |
| M.Wt | 182.24 |
| Cas No. | 284028-90-6 |
| Formula | C8H10N2OS |
| Solubility | ≥83.33 mg/mL in DMSO; ≥9.1 mg/mL in H2O |
| Chemical Name | 2-methyl-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one |
| Canonical SMILES | CC1=NC(=O)C2=C(N1)CCSC2 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
资料参考
Competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemiain vivoandin vitro. Brain penetrant.生物活性
| DR 2313 is a competitive inhibitor of PARP1 and PARP2 with IC50 of 0.20 and 0.24 μM respectively. |
| Targets | PARPK1 | PARP2 | | | | |
| IC50 | 0.20 μM | 0.24 μM | | | | |
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