化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 351.44 |
Cas No. | 94497-51-5 |
Formula | C22H25NO3 |
Synonyms | Am80;Am 80;Am-80 |
Solubility | insoluble in H2O; ≥13.35 mg/mL in DMSO; ≥52.5 mg/mL in EtOH with ultrasonic |
Chemical Name | 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid |
Canonical SMILES | CC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.