(Z)-9-Propenyladenine 是富马酸替诺福韦二吡呋酯中的诱变杂质。替诺福韦是一种抗逆转录病毒药物,是核苷酸类似物逆转录酶(NtART)抑制剂,能阻断HIV-1和HBV的逆转录酶。
Cas No. | 1464851-21-5 |
别名 | (Z)-替诺福韦酯杂质; (Z)-Mutagenic Impurity of Tenofovir Disoproxil |
Canonical SMILES | NC1=C2N=CN(/C=C\C)C2=NC=N1 |
分子式 | C8H9N5 |
分子量 | 175.19 |
溶解度 | DMSO: ≥ 100 mg/mL (570.81 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. |