您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > 5-hydroxy-6-methoxy(S)-Duloxetine
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
5-hydroxy-6-methoxy(S)-Duloxetine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
5-hydroxy-6-methoxy(S)-Duloxetine图片
CAS NO:741693-79-8
包装:1mg
市场价:3251元

产品介绍
5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine.
Cas No.741693-79-8
别名度洛西汀杂质
Canonical SMILESCNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C(O)C(OC)=CC=C32
分子式C19H21NO3S
分子量343.4
溶解度Chloroform: slightly soluble,Methanol: slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.