| CAS NO: | 1539314-06-1 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 330.3 |
| Cas No. | 1539314-06-1 |
| Formula | C14H13F3N2O2S |
| Solubility | ≤20mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide |
| Chemical Name | 1-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile |
| Canonical SMILES | CS(C[C@@H](C)N1C2=CC=C(C#N)C(C(F)(F)F)=C2C=C1)(=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
GSK2881078 is a potent and selective androgen receptor modulator (SARM) [1].
Steroidal nuclear receptor (NR) ligands play important roles in the health of both men and women. Dihydrotestosterone (DHT) and testosterone (T) are endogenous steroidal ligands for the androgen receptor (AR) that play a role in every tissue type found in the mammalian body. During the development of the fetus, androgens play an important role in sexual differentiation and development of male sexual organs. SARMs are small molecule pharmacotherapeutics that have the potential to afford the important benefits of androgen therapy without the undesired side-effects [1].
GSK2881078 is a potent and selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function. GSK2881078 is currently in phase I clinical trials [1].
Reference:
[1]. https://newdrugapprovals.org/2016/06/14/gsk-2881078/
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