Cardiogreen

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Cardiogreen

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

3599-32-4

包装与价格：

包装	价格(元)
100mg	电议
500mg	电议

产品介绍

化学性质

Storage	Store at -20°C
M.Wt	774.96
Cas No.	3599-32-4
Formula	C₄₃H₄₇N₂NaO₆S₂
Synonyms	Foxgreen; IC Green; Indocyanine green
Solubility	insoluble in EtOH; ≥17.17 mg/mL in H2O; ≥27.65 mg/mL in DMSO
Chemical Name	sodium 4-(2-((1E,3E,5E,7E)-7-(1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-2(3H)-ylidene)hepta-1,3,5-trien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate
Canonical SMILES	O=S(CCCCN(C1=C(C/2(C)C)C3=CC=CC=C3C=C1)C2=C\C=C\C=C\C=C\C4=[N+](CCCCS([O-])(=O)=O)C5=C(C6=CC=CC=C6C=C5)C4(C)C)([O-])=O.[Na+]
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

Cardiogreen, also known as indocyanine green, is a nontoxic tricarbocyanine dye, with a peak spectral absorption at 790 nm. Cardiogreen administered intravenously rapidly binds to its principle carrier, plasma protein, and then becomes confined to the vascular space. Cardiogreen has been commonly used in medical diagnostics for measuring cardiac output, liver blood flow, and hepatic function, as well as for ophthalmic angiography. In addition, cardiogreen can also be used as a photosensitizer in the photodynamic therapy (PDT) for treating diseases like periodontal infections.

References:

1. "Indocyanine green solution". NIH. National Cancer Institute. Retrieved 20 August 2021.

2. Gharesi S, Pourhajibagher M, Chiniforush N, et al. Effect of photodynamic therapy based on indocyanine green on expression of apoptosis-related genes in human gingival fibroblast cells. Photodiagnosis and Photodynamic Therapy , 2017, 19: 33-36.

试验操作

Cell experiment:[2]
Cell lines	Human gingival fibroblast (HGF) cells
Reaction Conditions	1000 μg/mL cardiogreen for 5 min incubation
Applications	Cardiogreen PDT with the exposure time of 60s for the diode laser would appear to be an inducer of apoptosis in HGF cells at transcriptome level.
Note	The technical data provided above is for reference only.
	References: 1. "Indocyanine green solution". NIH. National Cancer Institute. Retrieved 20 August 2021. 2. Gharesi S, Pourhajibagher M, Chiniforush N, et al. Effect of photodynamic therapy based on indocyanine green on expression of apoptosis-related genes in human gingival fibroblast cells. Photodiagnosis and Photodynamic Therapy , 2017, 19: 33-36.