| CAS NO: | 120330-93-0 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 323.43 |
| Cas No. | 120330-93-0 |
| Formula | C18H29NO4 |
| Solubility | ≤30mg/ml in ethanol;16mg/ml in DMSO;25mg/ml in dimethyl formamide |
| Chemical Name | (2S,3S)-3-methyl-2-(2-((1R,2R)-3-oxo-2-((Z)-pent-2-en-1-yl)cyclopentyl)acetamido)pentanoic acid |
| Canonical SMILES | C[C@@H](CC)[C@@H](C(O)=O)NC(C[C@H]([C@H]1C/C=C\CC)CCC1=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
(±)-Jasmonic Acid-Isoleucine is a plant hormone, formed by the conjugation of jasmonic acid and the amino acid isoleucine [1].
(±)-Jasmonic Acid-Isoleucine functions through a co-receptor complex consisting of the JAsmonate ZIM-domain (JAZ) repressor proteins and an E1 ubiquitin ligase complex containing the F-box Coronatine Insensitive 1 (COI1). Activation of the COI1-JAZ complex triggers the degradation of the JAZ protein, resulting in the release of transcription factors initially bound and inhibited by JAZ [1, 2]. (±)-Jasmonic Acid-Isoleucine is involved in several aspects of plant growth and development, and levels increased under stress conditions lead to the production of defense compounds and inhibition of growth [2].
In leaf extracts from a35S-COI1–Myc transgenic line of tomato, interaction of tomato COI1 with divergent members of the JAZ family was promoted specifically by (±)-Jasmonic Acid-Isoleucine and structurally related jasmonate conjugates at the concentrations of 1 or 10 μM. However, coronatine (COR) was ~ 1000-fold more active than (±)-Jasmonic Acid-Isoleucine in promoting this interactionin vitro [3].
References:
[1]. Katsir L, Chung H S, Koo A J K, et al. Jasmonate signaling: a conserved mechanism of hormone sensing. Current Opinion in Plant Biology, 2008, 11(4): 428-435.
[2]. Goossens J F, Fernández-Calvo P, Schwizer F, et al. Jasmonates: signal transduction components and their roles in environmental stress responses. Plant Molecular Biology, 2016, 91(6): 673-689.
[3]. Katsir L, Schilmiller A L, Staswick P E, et al. COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105(19): 7100-7105.
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