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L-5-Hydroxytryptophan
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
L-5-Hydroxytryptophan图片
CAS NO:4350-09-8
包装与价格：
包装价格(元)
Free Sample (0.1-0.5mg)电议
10mM (in 1mL DMSO)电议
100mg电议
200mg电议
500mg电议

产品介绍
L-5-Hydroxytryptophan (L-5-HTP) 是一种天然氨基酸和膳食补充剂，可作为抗抑郁剂、食欲抑制剂和睡眠辅助剂，是神经递质血清素的前体，是利血平 (reserpine) 的拮抗剂。L-5-Hydroxytryptophan (L-5-HTP) 可用于治疗纤维肌痛症、肌阵挛、偏头痛和小脑共济失调。
Cas No.4350-09-8
别名5-羟基色氨酸; L-5-HTP; Oxitriptan
Canonical SMILESN[C@@H](CC1=CNC2=CC=C(O)C=C12)C(O)=O
分子式C11H12N2O3
分子量220.22
溶解度DMSO: 100 mg/mL (454.09 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. Human Endogenous Metabolite

[1]. ARVID CARLSSON, et al. 3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists. Nature 180, page1200 (1957). [2]. Caruso I, et al. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18(3):201-9. [3]. Thal LJ, et al. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol. 1980 Jun;7(6):570-6. [4]. Boiardi A, et al. 5-OH-Tryptophane in migraine: clinical and neurophysiological considerations. J Neurol. 1981;225(1):41-6. [5]. Trouillas P, et al. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A double-blind study with quantified data processing. Arch Neurol. 1988 Nov;45(11):1217-22.