您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Odiparcil
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Odiparcil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Odiparcil图片
CAS NO:137215-12-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Odiparcil (SB-424323) 是一种具有口服活性 beta-d-thioxyloside 类似物,具有抗血栓形成活性,可降低不良出血事件的风险,Odiparcil (SB-424323) 是一种间接凝血酶抑制剂,通过激活抗凝血酶 II (肝素辅助因子 II) 发挥其抗凝血作用。
Cas No.137215-12-4
别名SB-424323
Canonical SMILESO=C1OC2=CC(OC3[C@H](O)[C@@H](O)[C@H](O)CS3)=CC=C2C(C)=C1
分子式C15H16O6S
分子量324.35
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2]. Thrombin[2]

[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70 [2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.