| CAS NO: | 50-53-3 |
| 包装 | 价格(元) |
| 1g | 电议 |
| 5g | 电议 |
| Storage | Store at -20°C |
| M.Wt | 318.86 |
| Cas No. | 50-53-3 |
| Formula | C17H19ClN2S |
| Solubility | ≥64mg/mL in DMSO |
| Chemical Name | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine |
| Canonical SMILES | ClC1=CC(N2CCCN(C)C)=C(C=C1)SC3=C2C=CC=C3 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Chlorpromazine is a member of the typical antipsychotic or neuroleptic drug class (also known as first-generation antipsychotics), used to manage and treat schizophrenia, bipolar disorder, as well as acute psychosis. Chlorpromazine exerts its antipsychotic effect by the post-synaptic blockade at the dopamine D2 receptors in the mesolimbic pathway. Also, chlorpromazine exhibits antiemetic effect by the combined blockade at dopamine D2, histamine H1, and muscarinic M1 receptors in the vomiting center, extending its indications for alleviation of nausea and vomiting. Chlorpromazine is commonly present as the hydrochloride salt in oral and injectable forms, and as the base in the suppositories.
Reference:
1. Mann SK, Marwaha R. Chlorpromazine. [Updated 2021 May 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan.
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