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RV01
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RV01图片
CAS NO:1016897-10-1
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
RV01 是白藜芦醇类似物,可抑制 DNA 损伤,降低乙醇诱导的乙醛脱氢酶 (ALDH2) 的 mRNA 表达,具有清除羟自由基的活性。RV01 降低 iNOS 的表达,具有抗神经炎症作用。
Cas No.1016897-10-1
Canonical SMILESOC1=CC(/C=C/C2=CC=NC3=CC=CC=C23)=CC(O)=C1
分子式C17H13NO2
分子量263.29
溶解度DMSO: 5 mg/mL (18.99 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity[1]. RV01 decreases iNOS expression, with anti-neuroinflammatory activity[2].

[1]. Yan Y, et al. Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Mutat Res. 2011 Apr 3;721(2):171-7. [2]. Hou Y, et al. A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways. Mol Nutr Food Res. 2019 Aug 4:e1801380.